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Product Name: Cetirizine Hydrochloride
Cetiizine dihydrochloride; Cetrizine dihydrochloride; Cetiizine dihydrochloride; Cetirizine dihydrochloride; (2- {4 - [(4-Chlorophenyl) (phenyl) methyl] piperazin-1-yl} ethoxy) acetic acid dihydrochloride
CAS Registry Number: 83881-52-1
Molecular formula: C21H25ClN2O3 · 2HCl
Molecular weight: 461.82
If you couldn't find the product you want in our store, maybe we haven't uploaded the complete product, please feel free to contact us through various ways; if you want to customize and process the product you want, please feel free to contact us for more details too.Cetirizine is mainly used for the treatment of seasonal and perennial allergic rhinitis, rhinoconjunctivitis, urticaria, allergic reactions caused by the bites of medicines, foods and insects.
Cetirizine is the metabolite of hydroxyzine in human body. Animal experiments show that cetirizine hydrochloride is a peripheral H1 receptor antagonist, which can inhibit the delivery and the effect of histamine, and can also inhibit the participation of vasoactive peptides And substance P, reduce the movement of inflammatory cells, effectively inhibit skin allergies. It can significantly reduce the tracheal allergic reaction caused by histamine in patients with asthma and reduce the allergic reaction caused by specific allergens. No significant anticholinergic and anti-serotonin effects. In clinical studies, it was found that the more common side effect of cetirizine than placebo was dry mouth. In vitro receptor binding studies have shown no significant affinity with other H1 receptors. In the effective dose, not easy to pass the blood-brain barrier, and will not affect the central nervous system and side effects.