Product Description
Product Name:FlibanserinCAS:167933-07-5Molecular Formula:C20H21F3N4OMolecular Weight:390.4EINECS: 643-002-2
A new drug designed to boost sexual desire in women is controversial for some and eagerly awaited by others, but it's hit a potentially serious snag. The drug didn't boost women's desire any more than a placebo in two clinical trials. The Food and Drug Administration posted the clinical trial results on its website today in advance of a committee meeting on Friday, when a panel of experts will vote whether or not to recommend approval of the drug called flibanserin. (The FDA usually follows the recommendations of its expert panels. ) Although there was a slight increase in the number of sexually satisfying events flibanserin users had each month, the FDA staff who reviewed the results said the so-called response rate isn't "particularly compelling.
Function
Flibanserin is used for hypoactive sexual desire disorder among women. Those receiving flibanserin report a 0.5 increase compared to placebo in the number of times they had "satisfying sexual events".In those on flibanserin it rose from 2.8 to 4.5 times a month while women receiving placebo reported also an increase of "satisfying sexual events" from 2.7 to 3.7 times a month.The onset of the flibanserin effect was seen from the first timepoint measured after 4 weeks of treatment and maintained throughout the treatment period.The effectiveness of flibanserin was evaluated in three phase 3 clinical trials. Each of the three trials had two co-primary endpoints, one for satisfying sexual events (SSEs) and the other for sexual desire. Each of the 3 trials also had a secondary endpoint that measured distress related to sexual desire. All three trials showed that flibanserin produced an increase in the number of SSEs and reduced distress related to sexual desire. The first two trials used an electronic diary to measure sexual desire, and did not find an increase. These two trials also measured sexual desire using the Female Sexual Function index (FSFI) as a secondary endpoint, and an increase was observed using this latter measure. The FSFI was used as the co-primary endpoint for sexual desire in the third trial, and again showed a statistically significant increase.
Application
Flibanserin is used for hypoactive sexual desire disorder among women. Those receiving flibanserin report a 0.5 increase compared to placebo in the number of times they had "satisfying sexual events".In those on flibanserin it rose from 2.8 to 4.5 times a month while women receiving placebo reported also an increase of "satisfying sexual events" from 2.7 to 3.7 times a month.The onset of the flibanserin effect was seen from the first timepoint measured after 4 weeks of treatment and maintained throughout the treatment period.The effectiveness of flibanserin was evaluated in three phase 3 clinical trials. Each of the three trials had two co-primary endpoints, one for satisfying sexual events (SSEs) and the other for sexual desire. Each of the 3 trials also had a secondary endpoint that measured distress related to sexual desire. All three trials showed that flibanserin produced an increase in the number of SSEs and reduced distress related to sexual desire. The first two trials used an electronic diary to measure sexual desire, and did not find an increase. These two trials also measured sexual desire using the Female Sexual Function index (FSFI) as a secondary endpoint, and an increase was observed using this latter measure. The FSFI was used as the co-primary endpoint for sexual desire in the third trial, and again showed a statistically significant increase.
Packing & DeliveryPayment Common Products100% payment before deliveryCOA offerCustom Synthesis Products30% deposit, 70% before deliveryTest report offerOur Company
Wuhan HengHeDa Pharm Co., Ltd is a hi-tech enterprise locates in Wuhan Private Science and Technology Park, specializing in custom synthesis, manufacture and import & export of fine chemicals, APIs and pharmaceutical intermediates. HengHeDa Pharm has complete administration management and a good work team, which makes it growing fast in chemicals and pharmaceutical industry.
Our Service
1.A novel R&D center with advanced ventilation equipments and modern experiment equipments.2.Two Large production factories with high capacity and meet the requirements of GMP.3.Supplying the products from our manufacturers;4.Custom synthesis of new products;5.Help sourcing products and suppliers in China;6.Assist the export and related affairs.7.Stable quality,professional production & technology; 8.The most competitive price;9.Steady supply, rapid delivery; 10.Perfect service, honest cooperation.
FAQ
1. Who we are?Wuhan hengheda pharm Co., Ltd., located in Wuhan, China, was founded in the year of 2013 by Dr. ZhouWe are now the few professional manufacturers for the series of natural high purity product, such as astragalus extract (Astragaloside IV and Cycloastragenol), Gardenia jasminoides Ellis extract (Genipin, Geniposide and Geniposidic acid) and Galangin in China.Dr Zhou majored in natural plant chemistry and new chemical synthesis , who was graduated from Shanghai Institute of Biology, Chinese Academy of Science.)2. Do we have the test reports for our products provided by the independent third party?Every batch of our product was tested by authorized independent third party, Analysis testing center, Shanghai branch, Chinese Academy of Science. We send goods to customers with test report and COA. Our products were also tested by American Analytical Chemistry Laboratories and Chromadex too.3. What is our advantage?The series of natural extracted product are all self-developed, produced and tested. Mature production technology, strict cost control, and perfect quality assurance system, ensure the product stability and competitive price.4. How we perform an order?Email inquiry is preferred in our company. We usually give our formal quotation list or formal reply within 24 hours including price, lead time and any other information customer needed. Our quotation is usually valid for three months.5. What is the minimum order quantity?No matter how much do you need, we all can supply you with the suitable package, from sample quantity to bulk order.