Factory sales 99% High Purity Sex Powder Vardenafil

Factory sales 99% High Purity Sex Powder VardenafilChemical information Product namevardenafilStorage3years-20°CpowderFormulaC23H32N6O4S.HCl.3H2O2years-80°CinsolventCASNo.330808-88-3SynonymsLevitraSolubility(25°C)*InvitroDMSO116mg/mL(200.3mM)Water116mg/mL(200.3mM)Ethanol20mg/mL(34.53mM)Invivo*<1mg/mlmeansslightlysolubleorinsoluble.
*PleasenotethatLongfineteststhesolubilityofallcompoundsin-house,andtheactualsolubility
maydifferslightlyfrompublishedvalues.Thisisnormalandisduetoslightbatch-to-batchvariations.Purity & Quality
VardenafilPurity(HPLC):
99.98%VardenafilIdentity (NMR):
Consistent with structure
HPLC spectrum of vardenafilpowder
Proton NMR Spectrum ofvardanafilpowderBiological Activity DescriptionVardenafil HCl Trihydrate is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.In vitroVardenafil specifically inhibits the hydrolysis of cGMP by PDE5 with an IC50 of 0.7 nM (6.6 nM). Vardenafil significantly enhances the SNP-induced relaxation of human trabecular smooth muscle at 3 nM (10 nM). Vardenafil also significantly potentiates both ACh-induced and transmural electrical stimulation-induced relaxation of trabecular smooth muscle. Vardenafil (100 mM) increases cyclic GMP levels in rat hippocampal slices. Vardenafil, tadalafil, and Sildenafil each competitively inhibit cGMP hydrolysis by phosphodiesterase-5 (PDE5), thereby fostering cGMP accumulation and relaxation of vascular smooth muscle.In vivoVardenafil dose-dependently potentiates erectile responses to intravenously administered sodium nitroprusside in rabbit. Vardenafil (3 mg/kg, p.o.) results in an improved object discrimination performance in rats. Vardenafil (30 mg/L, p.o.) increases both iNOS and proliferating cell nuclear antigen expression (SM cell replication) in rats, with normalization of the dynamic infusion cavernosometry drop rate and SM/collagen ratio. Vardenafil induces powerful preconditioning-like cardioprotective effect against ischemia/reperfusion injury through opening of mitochondrial K(ATP) channels in the heart of rabbit. Vardenafil protects the ischemic myocardium against reperfusion injury through a mechanism dependent on mitochondrial K(ATP) channel opening.Buying GuidesFAQ
Q1: Can i get some samples?
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2: How to start orders or make payments?
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, Western Union or Paypal or Escrow(Alibaba).
Q3: How to confirm the Product Quality before placing orders?
A:You can get free samples for some products,you only need to pay the shipping costor arrange a couriertous and take the samples.
You can send us your product specifications and requests,we will manufacture theproducts according to your requests.
Q4:What’syourMOQ?
A:OurMOQis1kg.Butusuallyweacceptlessquantitysuchas100gontheconditionthatsamplechargeis100%paid.
Q5:Howaboutdeliveryleadtime?
A:Deliveryleadtime:about3-5 daysafterpayment /confirm/ied.(Chineseholidaynotincluded)
Q6:Is there a discount?
A:Different quantity has different discount.
Q7: How do you treat quality complaint?
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
Q8: How to contact us ?
A:You can chat with us by Trademanager,MSN&Skype Online.
You can choose your interested products and send inquiry to us.
You can dial our telephone directly, you will get our reply.
Send Email to us.Contact us