Product NameAdemetionine 1,4-butanedisulfonateOther NameSAMeAppearanceWhite to off-white powderCAS NO.101020-79-5Molecular FormulaC19H32N6O10S3Molecular Weight1451.63
Ademetionine 1,4-butanedisulfonate is the 1,4-butanedisulfonatemixed sodium salt of a mixture of diastereoisomers of the ademetionine ions.What is SAMe?
SAMe is a molecule that is formed naturally in the body. It can also be made in the laboratory. SAMe is involved in the formation, activation, or breakdown of other chemicals in the body, including hormones, proteins, phospholipids, and certain drugs.SAMe has been available as a dietary supplement in the US since 1999, but it has been used as a prescription drug in Italy since 1979, in Spain since 1985, and in Germany since 1989.SAMe is used by mouth fordepression,anxiety,heart disease,fibromyalgia,abdominal pain,osteoarthritis,bursitis, tendonitis, chroniclower back pain,dementia,Alzheimer's disease, slowing theagingprocess,chronic fatigue syndrome(CFS), improving mental performance,liver disease, andParkinson's disease. It is also used for attention deficit-hyperactivitydisorder (ADHD),multiple sclerosis,spinal cordinjury,seizures,migraine headache,lead poisoning, to break down a chemical in the body called bilirubin, or to help with disorders related to the buildup of a chemical called porphyrin or its precursors.Some women take SAMe by mouth forpremenstrual syndrome(PMS) and a more severe form ofPMScalledpremenstrual dysphoric disorder(PMDD).SAMe is used intravenously (by IV) fordepression,osteoarthritis,AIDS-relatednervous systemdisorders,fibromyalgia,liver disease,cirrhosis, and for aliverdisorder that occurs inpregnantwomen calledintrahepaticcholestasis.SAMe is injected as a shot forfibromyalgia,depression, andAlzheimer's disease.
Is SAMe effective?
SAMe can relieve depression and some fibromyalgia symptoms.
SAMe also seems to help protect the liver. People with liver disease in the early stages sometimes do better when they take SAMe and might even be able to delay the need for a liver transplant. But people with advanced liver disease are not as likely to be helped by taking SAMe.Effective for:
Depression.
Osteoarthritis.
Symptoms of AIDS-related nerve problem
Cirrhosis.
Fibromyalgia.
Condition in which the flow of bile from the liver is slow or blocked (Intrahepatic cholestasis).
Sexual dysfunction.