HA Sodium Hyaluronate Cosmetic grade

Sodium Hyaluronate is well known as the best “Natural Moisturizing Factor”. In the early 1980s, the excellent moisturizing function of Sodium Hyaluronate has been widely concerned by international cosmetics industry. With its unique film-forming and hydrating characteristics, Sodium Hyaluronate is used as a highly effective humectants in cosmetics. It attracts moisture to the skin and hold moisture in the skin, which preserve skin smoothness, suppleness and elasticity. 1 gram of HA is able to retain up to 1000 gram of water. So it is regarded as the “key to the fountain of youth”. The effects are as follows:
(1) Moisturizing effect
Moisturizing is the most important effect of Sodium Hyaluronate in cosmetics products. It can be hydrated shell in skin surface and make the corneum hydration and softening. Compared with other humectants, Sodium Hyaluronate is less effected by the environment as it has the highest hygroscopic capacity in a relatively low humidity (e.g., in a dry winter), but has the lowest hygroscopic capacity in a relatively high humidity (e.g., in a damp summer). This unique property of Sodium Hyaluronate makes the skin adapt to different seasons.
(2) Skin nutrition effect
Sodium Hyaluronate is the inherent biological materials of skin. The exogenous Sodium Hyaluronate can complement the endogenous Sodium Hyaluronate. Low molecular Sodium Hyaluronate can penetrate into dermis directly to improve the nutrient supply.
(3) Skin repair effect
There is some evidence that topically applied Sodium Hyaluronate can reduce skin irritation from various causes. During clinical trials it was also shown that this ingredient is effective in promoting healing and fighting inflammatory conditions of the skin. Sodium Hyaluronate serves as a free radical scavenger and antioxidant, helping to protect the skin from the aging effects of excessive sunlight exposure.
(4) Emollient and Film-forming
Sodium Hyaluronate is high polymer with high lubrication and film-forming. Sodium Hyaluronate contained in cosmetics creates protective film on the surface of skin, which retains moisture, and at the same time prevents moisture in the skin from evaporation, so that improves freshness of the skin.
(5) Thickening
Sodium Hyaluronate solution have high viscosity, and 1% solution is gelatinous. It can be added to cosmetics to improve the thickening and stability.
Cosmetic Benefits One of the principle characteristics of HA is its ability to retain water, which contributes significantly to the skin maintaining a youthful appearance. Like many other essential factors, the levels of HA in the body decreases with each passing year. As the levels of hyaluronic decrease it adversely impacts the skin's ability to retain moisture, thus leading to those inevitable wrinkles.
Hyaluronic acid supplements boast a number of benefits by supporting healthy skin function. Hyaluronic acid has the potential to help reproduce healthy skin cells within a collagen matrix by increasing hydration and acting as a lubricant among the collagen matrix of the skin. Given that Hyaluronic acid is an element of the skin's construction and weakens with age, the supplements help ensure ample levels stay in the skin to sustain its overall appearance and function.
The benefits of hyaluronic acid are becoming increasingly well known as an effective anti-aging skin care treatment in the skin care industry.
Item
Standard
Appearance
White powder
Solubility
Soluble in water, practically insoluble in acetone and in anhydrous ethanol.
Glucuronic Acid
Min.44%
Sodium Hyaluronate
Min.91%
Appearance of Solution
A600nm≤ 0.01
Nucleic Acid
A260nm≤ 0.5
pH
6.0-7.5
Molecular Weight
1.0-1.5 Million Daltons / 1.5-2.0 Million Daltons
Protein
Max.0.05%
Loss on drying
Max.10%
Residue on Ignition
Max.20%
Chlorides
Max.0.5%
Iron
Max.80ppm
Heavy metal
Max.20ppm
Arsenic
Max.2ppm
Nitrogen
3.0-4.0%
Bacteria Count
Max.10CFU/g
Molds & Yeast
Max.10CFU/g
Staphylococcus aureus
Negative
Pseudomonas aeruginosa
Negative
Hemolysis
Negative
Viable Hemolytical Streptococci
Negative
Specification of HA (Cosmetic Grade)
Items
Specifications
Cosmetic Grade HA
HA (Low Molecular Weight)
HA-Oligo
Description
White or off-white powder or granules
White or off-white powder or granules
White or off-white powder or granules
pH
6.0-7.5
6.0-7.5
3.0-5.0
Transparency
≥99%
≥99%
≥99%
Loss on drying
≤10.0%
≤10.0%
≤10.0%
Molecular weight
≥1,800K Da
10K Da - 1,000K Da
<10K Da
Protein
≤0.05%
≤0.05%
≤0.1%
Heavy metals
≤20ppm
≤20ppm
≤20ppm
Glucuronic acid
≥44.0%
≥44.0%
≥44.0%
Bacterial counts
≤100cfu/g
≤100cfu/g
≤100cfu/g
Mold and Yeast
≤10cfu/g
≤10cfu/g
≤10cfu/g
Pseudomonas aeruginosa
Negative
Negative
Negative
Staphylococcus aureus
Negative
Negative
Negative
Product FeaturesMolecular Weight (MW) and functions:
Name of products
MW Range
Functions
High Molecular Weight HA
≥1,800K Da
Excellent moisturizing, lubricating and film-forming properties on skin.
Medium Molecular Weight HA
1,000K Da - 1,800K Da
Moisturizing, film-forming and good skin-feel
Low Molecular Weight HA
10K Da - 1,000K Da
Penetrate the skin far easier
HA-Oligo
<10K Da
Penetrate better into skin and nourish the skin deeply
Application
Shelf life:
Product in powder or granular form should be 24 months.
1%solution should be 12 months.