Human Luteinizing Hormone In Vitro Diagnostic Reagent LH Elisa test kit

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Human Luteinizing Hormone In Vitro Diagnostic Reagent LH Elisa test kit
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Product nameDetection Kit Human Luteinizing Hormone LH By ELISA Test Infertility Kitbeijing,chinaMethodologyEnzyme-linked immunosorbent assay
Size
3.0mm/3.5mm
Storage
2-8℃ at room temperature
Shelf life
12-18Months
Brand Name
BNIBT
MOQ
50 boxes
Certification
CFDAAccuracyOver 99%Detection range2IU/L to 75IU/LIncubation1 hSample volume50μlPayment methodT/T, Western Union or Paypal are availableDelivery time3--25 days(As your order)Free samplesAvailableOther ServiceThe kits can be made according to the customers' artwork or design.
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Clinical significance:
Human Luteinizing Hormone (LH) is secreted by the b-cells of the anterior pituitary under the control of hypothalamic gonadotropin releasing hormone (GnRH). LH in the female causes ovulation and steroid (estrogen and progesterone) production by the corpus luteum. In the male it stimulates interstitial cells (Leydig cells) to produce androgens and estrogens. Circulating levels of LH are controlled by a negative feedback effect on the hypothalamus by the steroid hormones. In sexually mature adults, FSH and LH are not secreted in constant amounts; rather, secretion occurs in pulses which result in rapid fluctuations over the entire reference range (up or down by 50 to 100%). Because of this pulsatile secretion, samples obtained in a single day from the same patient may fluctuate widely within the reference range, reflecting physiological variation rather than errors in technique or methodology.
The primary clinical use of LH measurement is in clearly defining the hypothalamic-pituitary-gonadal axis. Measurement of serum gonadotropin levels will allow for distinguishing between primary gonadal failure and deficient gonadal stimulation. If LH and FSH levels are elevated (hypergonadotropic hypogonadism), primary gonadal failure is present. If, on the other hand, gonadotropin levels are low (hypogonadotropic hypogonadism), deficient gonadal stimulation has resulted in the hypogonadal state.
LH measurement is also of clinical importance because growth hormone and LH are frequently the first hormones to be affected by pituitary disease.
Serum determinations have been very useful in the diagnosis and treatment of infertility in women. A midcycle rise in the LH level is a good indication that ovulation will occur approximately 24 hours later. The reproductive phase in females is terminated by menopause, due to low levels of circulating estradiol and progesterone, there is a loss of negative feedback to the hypothalamus; as a result, circulating levels of LH are greatly increased. Similarly, LH levels are increased in younger women of premenopausal age who suffer ovarian failure or whose ovaries have failed to develop during puberty. It is important to note that the midcycle peak is completely obliterated in healthy women using oral contraceptives. Testosterone and estrogen administration depress LH levels in the post-menopausal state.
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