API raw material 99% Spironolactone/CAS 52-01-7/spironolactone powder
Name:Spironolactone
Cas No:52-01-7
MF:C24H32O4S
Use:diuretic agent
Appearance:white powder
Items
Specifications
Results
Description
White or almost white imperceptibility crystalline powder
White imperceptibility crystalline powder
Solubility
In easily dissolved in chloroform. In ethyl benzene or in soluble. Dissolved in ethanol. Insoluble in water
Meet the requirements
Identification
A. The IR chromatogram of the test sample should response to standard
Meet the requirements
B. Absorptivities at 238nm,calculated on the dried basis, do not differ by more than 3.0%
Meet the requirements
C.Color reaction
Meet the requirements
Specific rotation
Between -41°and -45°
-42°
Loss on drying
≤0.50%
0.2%
Limit of mercapto compounds
≤0.10ml
0.03ml
Ordinary impurities
Total impurities ≤2.0%
Meet the requirements
Residue solvents
Methanol
≤0.30%
Not detected
Assay(on the dried basis)
97.0%~103.0%(HPLC)
99.7%
Conclusion
Meet the requirements of USP35